So, what is Delta-8-THC? Delta-8-THC is one of the 100+ cannabinoids found in the cannabis plant. Like other cannabinoids, it interacts with the body’s endocannabinoid system – specifically the CB1 receptor of the nervous system – to produce a psychotropic effect. Delta-8-THC interacts with the nervous system similarly to Delta-9-THC to produce feelings of euphoria and uplifted mood as well as feelings of calmness and relaxation. Delta-8-THC also has antiemetic (anti-nausea), anxiolytic (anti-anxiety), orexigenic (appetite stimulant), analgesic (pain relieving), and neuroprotective properties.